There's an anti-wrinkle substance that decreases wrinkle depth and increases the smoothness of you skin. It's called Palmitoyl pentapeptide and in a study comparing it with retinal cream, it worked better and did not cause any irritation at all. Two products that already contain it are Olay's Regenerist Cream and L'Oreal's Plentitude Age Perfect Cream.
If you decide to experiment with it, let me know your results.
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