Saturday, July 23, 2022

The Original Research on Alzheimer’s Disease and Amyloid Plaques May Have Been Bogus

The new drug for Alzheimer’s Disease, called Aduhelm, while approved by the FDA, appears to not work. It’s premised on getting rid of the amyloid plaques in the brain. Most of the drugs in the pipeline to cure Alzheimer’s are also aimed at the plaques. Alzheimer’s drugs have an enormous failure rate of 99% in human trials!

So, here’s the problem, the original study done 16 years ago, which was done on mice, might have been doctored. Mathew Schrag, Vanderbilt University Neuroscientist, was hired by a group of scientists who had questions about the reliability of this study.

Schrag took a look at the original study’s research, and it looked to him that the original images had been altered. Some looked like they had been pieced together from multiple images. The journal Science did a six-month review of the images, where they consulted with image experts, and they agreed that there were shockingly blatant examples of image tampering.

These doctored images enabled the researchers to support their hypothesis about amyloid plaques being the basis of Alzheimer’s.

What this means is that all the research that has been done since then looking at amyloid plaques has been the equivalent of looking in the wrong place for an answer to the cause of Alzheimer’s. This means billions of dollars flushed down the tubes. It means people suffering and dying from Alzheimer’s.

I remember reading reports of autopsies being performed on people and finding people who had been diagnosed with Alzheimer’s disease not having any plaques and other people who maintained their mental facilities have a lot of amyloid plaques in their brains. The researchers, at the time, could not explain the differences they observed. 

The last piece relates to the NIH recently awarding a 5-year contract to study Alzheimer’s to the same researcher who published the original study. That grant was awarded by Austin Yang, program director at the NIH’s National Institute on Aging. It turns out that Yang also happens to be one of the co-authors on the original 2006 paper. 

So…I guess the NIH program director may be suffering from Alzheimer’s because he forgot that he participated in the original study and should have recused himself from making the decision in light of this new information!(Reported dailykos.com, Mark Sumner, July 22, 2022)


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